L - type voltage - gated calcium channels in depolarization shifts
نویسندگان
چکیده
A28 Current-clamp experiments on primary hippocampal neurons shed light on the role of L-type voltage-gated calcium channels in depolarization shifts Helmut Kubista, Lena Rubi, Petra Geier, Michael Lagler and Stefan Boehm Department of Neurophysiology and Neuropharmacology, Center for Physiology and Pharmacology, Medical University of Vienna, 1090 Vienna, Austria E-mail: [email protected]
منابع مشابه
Current-clamp experiments on primary hippocampal neurons shed light on the role of L-type voltage-gated calcium channels in depolarization shifts
Background Paroxysmal depolarization shifts are the cellular representations of interictal spikes. Interictal spikes (IIS) have a long history in the diagnosis of epilepsy. Previously, it was thought that IIS are largely asymptomatic, but there is growing evidence that beside being involved in epileptogenesis, they are also involved in the pathogenesis of various other neurological diseases. Ho...
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Ion channels are embedded in the lipid bilayer of cell membranes; therefore, it is not surprising that their functions can be modulated by membrane phospholipids and their metabolites. Over the last decade, a number of ion channels—including multiple types of potassium channels, voltage-gated calcium channels, and transient receptor potential channels—have been shown to be modulated by phosphol...
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تاریخ انتشار 2011